Swipe for 6 photos
Zero Exosome Shot
serum
Best trusted price
$42.00$50.0016% off MSRP
at medicube
+$6.99 shipping, free on orders over $80
Go to medicubeWe started tracking this product recently. Price insights appear after a week of history.
Compare prices from 1 store
Updated every 6 hours · shipping for this item alone
- MSRPBrand list price (before sales)$50.00

medicubeOfficial brand storeBest price
In stock · +$6.99 shipping · free over $80
Visit store$42.00
16% below MSRP
Not price-tracked yet: Search Amazon · Search Ulta · Search Target
Price history
- Current
- $42.00
- medicube
- Lowest
- $42.00
- Oct 29, 2026 · medicube
- Highest
- $42.00
- Oct 29, 2026
- Average
- $42.00
- since Oct 29, 2026
Details
- Brand
- medicube
- Routine step
- Treat
- Type
- serum
- MSRP
- $50.00
Sizes at the brand store
- MILD(2000) · $22.00
- STRONG(7500) · $24.00
- INTENSE(25000) · $26.00
About this product
OVERVIEW
Tingling Ampoule
Tingling sensation is natural. You may experience a tingling sensation,
which may last for some time, but rest assured that this is a natural
reaction to the Zero Exosome Shot.
Drawing upon the principles of microneedling, we've crafted a
micro-sized, needle-shaped booster to target a range of skin issues.
Enhanced with 15M patented Exosome shots, this formula physically
delivers active ingredients to pores, providing daily intensive
treatments for home use. Clinically validated to care for pore size,
smooth skin texture, strengthen the skin barrier, and promote a radiant
complexion.
Non-comedogenic
Tested to be Low-Irritating
Gluten-Free
No artificial color
Net wt. 1.01 fl. oz. / 30ml
STUDY RESULTS
Results from a consumer use study
100%
Feels like receiving professional care, providing a pleasant sensation.
Overall product satisfaction.
Positive feedback from a 20-person survey, with individual variances.
Tested by the Global Institute of Dermatological Science.
Test period: August 24, 2022 - September 21, 2022.
Results from a self test report
Absorption of active ingredients
Absorption of active ingredients in cosmetics compared to standalone use
+242%
Pore Care Effect
Pore density care -21.1%
Decrease in pore visibility -21.1%
Pore area -15.3%
Pore volume -16.7%
Other skin enhancements
Dead Skin Cells improvement +88.7%
Enhancement of radiance +51.7%
Sebum improvement +8.9%
Surface hydration enhancement…
How to use
BEGINNER If you are not familiar with skincare products containing spicules, we do not recommend using them with our AGE-R devices. Step 1. After cleansing, prepare your skin with Meicube's Zero Pore Pads (or other hydrating toners). Step 2. Apply the Zero One Day Exosome Shot to the desired area (e.g., areas with uneven texture, enlarged pores, etc.) and gently rub and press to aid absorption. Step 3. Finish with Medicube's Collagen Jelly Cream (or your daily water-based moisturizer). STANDARD Step 1. After cleansing, apply the Zero One Day Exosome Shot to your entire face, avoiding the area near your eyes and lips. For the best results, we recommend using the Exosome Shot as the first step in your skincare routine. Step 2. Gently rub and press with your hands to ensure that the…
Full ingredients
Show all ingredients (INCI, as listed by the brand)
, which may cause a tingling sensation upon application. This is a natural reaction as the active ingredients are being delivered to the pores. We recommend adjusting the amount and frequency of use based on individual skin sensitivity. Q. Do I simply wash it off or do I maintain my regular skincare routine afterwards? This product is not meant to be rinsed off. Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone. Q. What are exosomes, and what is the source and function of the Lacto Exosome in Zero Exosome Shot? Exosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information (like RNA). The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps boost the immune system. Q. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed? The spicules are designed to naturally shed along with the dead skin over several days after application. Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate. Q. Are there any ingredients that should not be used together with it? There are no specific ingredients that should not be used together; however, individuals with sensitivity should be cautious as certain may cause irritation or hypersensitivity reactions. Please conduct a patch test and adjust the amount and frequency of use accordingly. Q. I want to focus on managing my pores. Are there any synergistic products that work well together? When used in conjunction with the Exosome Shot, the One-day Serum and One-day Cream result in an 88% improvement in pore volume and an 85% improvement in pore area compared to using the Exosome Shot alone. For more effective pore management, we recommend using the Exosome Shot Ampoule first, followed by the One-day Serum, and finishing with the One-day Cream. Excerpts from in vivo absorption tests for improving skin absorption depth compared to using One-day Serum + One-day Cream alone. / Individual results may vary.
Product information from the medicube store. Prices can change at any time; check the store before you buy.





